Comparison

Best longevity blood tests
2026 full comparison.

Six services, one honest breakdown. Superpower, Function Health, InsideTracker, OneTwenty, Marek Health, and Ulta Lab Tests — what each costs, what you actually get, and who each one is right for.

Updated May 2026
Reading time ~10 min
Affiliate Disclosed

At a glance

The direct-to-consumer biomarker testing market has consolidated around a handful of meaningful options. The table below covers the six services worth considering in 2026 — organized by what they are and what they cost.

Service Price Draws/yr Biomarkers ApoB Lp(a) Cancer mkrs Rx access Best for
Superpower $199/yr 1 100+ (150 w/ratios) Add-on Entry-level longevity baseline
Function Health $365/yr 2 160+ Comprehensive annual monitoring
InsideTracker $149–$489/yr 1–2 Up to 48 Higher tiers Athletic optimization + DNA
OneTwenty $499/yr 4 (quarterly) 78 baseline + targeted Selected panels Continuous care + coaching
Marek Health $450–$2,000/draw As needed 65–100+ per tier Clinical optimization + TRT
Ulta Lab Tests À la carte Unlimited Any combination Selected tests Custom panels, max flexibility
Affiliate disclosure

AgelessLabs has affiliate relationships with Superpower and Ulta Lab Tests. We may earn a commission if you purchase through those links — at no additional cost to you. All assessments reflect our independent analysis.

The services, in depth

Function Health
Best comprehensive panel for active management
$365
/ year · 2 draws

Function Health is the most thorough consumer biomarker service at a non-concierge price. Two annual draws, 160+ directly measured markers, cancer screening markers (PSA, CEA, AFP, CA-125), heavy metals (lead, mercury, arsenic), ANA autoimmune screen, and Lp(a) and omega-3 index included in the base panel. The twice-yearly cadence is the key differentiator — the only service in this price range that enables a test-intervene-retest loop within a single membership year. Trade-offs: no historical lab import, the AI protocol builder is newer than Superpower’s, and there is no home draw option. Founded by Dr. Mark Hyman and backed by $298M in Series B funding.

2Annual draws
160+Direct biomarkers
$365Reduced from $499
NY/NJ/RINot available
Visit Function Health → Full Review →
InsideTracker
Best for athletic optimization and DNA integration
$149–$489
/ year · varies by tier

InsideTracker, founded in 2009 by researchers from MIT and Tufts University, was the original direct-to-consumer biomarker platform. Its differentiation today lies in DNA integration (genetic testing layered with blood data), wearable sync (Apple Watch and others), and a legacy of longevity science credibility. The marker breadth is narrower than Function or Superpower — up to 48 biomarkers on the Ultimate tier — but the action plan quality and InnerAge biological age calculation are well-regarded. Pricing is tiered and adds up quickly: the $149/year membership covers platform access only; actual testing runs $340–$489 additional depending on panel. Total annual cost for a serious user is $489–$638.

Up to 48Biomarkers (Ultimate)
$489+Total cost with testing
DNA add-onAvailable
WearablesApple Watch + others
Visit InsideTracker →
OneTwenty
Best continuous care system (beta)
$499
/ year · quarterly draws

OneTwenty (formerly Outlive.bio) is the most integrated option in this comparison — less a pure testing service and more a continuous health optimization system. The $499/year Core membership includes quarterly biomarker testing (78 markers at baseline, then 20–40 targeted markers every 90 days), AI health coaching, wearable data integration (syncing continuous signals from Oura, Whoop, Apple Watch), and access to affiliated physicians who can prescribe when warranted. It is currently in beta, with full launch expected July 2026. The quarterly testing cadence is meaningful: it’s the only service that enables rapid intervention tracking. Trade-offs: newer platform with less track record, beta-stage product polish, and prescription access varies by state.

4Quarterly draws
78 baseline+ targeted markers
Rx accessVia affiliated physicians
BetaFull launch July 2026
Visit OneTwenty →
Marek Health
Best for clinical optimization with physician oversight
$450–$2,000
/ draw · à la carte

Marek Health is a different category from the services above — a telehealth clinical optimization practice, not a pure testing subscription. Founded by Derek from More Plates More Dates on the premise that you cannot optimize what you do not measure, Marek pairs comprehensive LabCorp panels with physician and health coach oversight and the ability to prescribe treatments (TRT, peptides, GLP-1s, thyroid, and more). Four panel tiers: Base ($250), Comprehensive ($450), Complete ($850), and Executive ($2,000). A key technical differentiator: Marek uses LC/MS (liquid chromatography-mass spectrometry) for testosterone and estradiol — significantly more accurate than standard immunoassays, particularly important for women and anyone on hormone therapy. Annual costs for a managed patient easily reach $1,000–$2,500 between panels and consultation fees. Right for someone who wants a clinician actively managing their optimization protocol. Not the right fit if you just want data.

On-demandNo annual commitment
LC/MSHigher-accuracy hormones
Rx accessTRT, peptides, GLP-1
47 statesNot NY/NJ/RI
Visit Marek Health →

Which service wins by category

Best overall value
Superpower — $199/yr
Covers the longevity fundamentals at the lowest annual price. Right for most people starting a biomarker practice.
Most comprehensive panel
Function Health — $365/yr
160+ directly measured markers, two annual draws, cancer markers, heavy metals. Nothing else competes at this price.
Best for tracking interventions
OneTwenty — $499/yr
Quarterly draws enable rapid intervention feedback. Function Health's two draws are the runner-up for this use case.
Best for athletic performance
InsideTracker — $489+/yr
DNA integration, wearable sync, and a longevity science pedigree built around performance optimization.
Best clinical oversight
Marek Health — $450+/draw
The only option with genuine physician management, LC/MS hormone accuracy, and prescription access. Costs accordingly.
Best for custom or frequent testing
Ulta Lab Tests — à la carte
No subscription, no dashboard, no guesswork. Order exactly what you need, as often as you need it.

How to choose

Start here if you’ve never done comprehensive testing

Superpower at $199/year is the right entry point for most people in this situation. It covers the markers that matter most for longevity — ApoB, full hormone panel, thyroid, inflammatory markers, nutritional status — at a price that makes it easy to commit. The biological age score and polished dashboard make results easy to act on. You can always upgrade to Function Health after you have a baseline and understand what you want to track more closely.

Choose Function Health if you’re actively managing your health

The twice-yearly draw is what separates Function from everything in its price range. If you’re working on a specific cardiovascular marker, adjusting hormone protocols, or supplementing based on deficiencies, the mid-year retest is the only way to know whether anything worked within a single year. Function also belongs at the top of the list for anyone who wants cancer marker screening or heavy metal testing as part of their annual workup.

Choose OneTwenty if you want a full system, not just data

OneTwenty is built around the idea that testing alone isn’t enough — what matters is continuous feedback and guided action. If you want quarterly testing, AI coaching that integrates your wearable data, and physician access for prescription optimization, OneTwenty is the most complete product in this space. The caveat is that it’s still in beta as of mid-2026, and newer platforms carry product maturity risk.

Choose InsideTracker if you’re performance-focused

InsideTracker’s strengths are its athletic performance orientation, its DNA add-on (which layers genetic data with blood results for more personalized recommendations), and its wearable integrations. If you’re training seriously and want a platform built around performance optimization rather than longevity risk reduction, InsideTracker is the best fit. Be aware that the total annual cost including testing is $489–$638 — higher than the membership price alone suggests.

Choose Marek Health if you want clinical management, not just data

Marek Health is for someone who wants a physician actively involved in interpreting results and prescribing protocols — TRT, peptides, thyroid optimization, or GLP-1 weight management. The testing panels are excellent and the LC/MS hormone methodology is more accurate than what subscription services use. But the annual cost is substantially higher, and the model works best for someone already committed to an active optimization protocol.

Use Ulta Lab Tests for flexibility and frequency

If you already know which markers you want, if you need to test more than twice per year, or if you want to verify specific results from another service, Ulta Lab Tests is the right tool. There is no dashboard or interpretation layer — results come raw. Pair it with our AI biomarker interpreter to get longevity-optimal range analysis on whatever you order.

State availability

Most of these services are unavailable or priced differently in New York, New Jersey, and Rhode Island due to state regulations on direct-to-consumer lab testing. Superpower charges $399/year (vs. $199) in NY and NJ. Function Health, InsideTracker, and Ulta Lab Tests are generally not available in those states. Marek Health operates in 47 states. Confirm availability at each service’s website before purchasing.

Already have results from any of these services?

Upload or paste your labs into our AI tool for a longevity analysis — every marker scored against longevity-optimal ranges, not just standard lab reference ranges. Works with results from any service.

Analyze My Labs →

Frequently asked questions

What is the best blood test for longevity?
Depends on your situation. For a first comprehensive baseline at the lowest price: Superpower at $199/year. For the most complete panel with twice-yearly testing: Function Health at $365/year. For à la carte testing without an annual commitment: Ulta Lab Tests. For continuous coaching and quarterly draws: OneTwenty. The markers that matter most for longevity are ApoB, Lp(a), fasting insulin, hsCRP, homocysteine, Vitamin D, and a full hormone and thyroid panel.
Is Function Health or Superpower better?
Superpower is better if you want the longevity fundamentals at the lowest price (one annual draw, $199). Function Health is better if you need twice-yearly testing, cancer markers, or heavy metal screening ($365, two draws, 160+ directly measured biomarkers). For a first draw, Superpower. For active health management, Function. See the full Function Health review and Superpower review for the detailed comparison.
How much does a comprehensive longevity blood test cost?
Annual subscriptions range from $199 (Superpower) to $365 (Function Health) to $499 (InsideTracker Ultimate, OneTwenty). À la carte testing through Ulta Lab Tests covers the same longevity markers for $150–$300 with no annual commitment. Marek Health is in a different category — panels run $450–$2,000 plus consultation fees, suited for clinical optimization rather than self-directed testing.
What is OneTwenty Health?
OneTwenty (formerly Outlive.bio) is a health optimization platform combining quarterly biomarker testing, AI coaching, wearable data integration, and prescription access via affiliated physicians. At $499/year it is the most integrated service in this comparison. Currently in beta, with full launch expected July 2026.
Can I do a longevity blood test without a doctor?
Yes. Superpower, Function Health, InsideTracker, OneTwenty, and Ulta Lab Tests all allow adults to order comprehensive biomarker panels directly without a physician referral. You purchase online, visit a Quest Diagnostics or LabCorp draw site, and receive results through the platform. Most are not available in New York, New Jersey, or Rhode Island.
What biomarkers matter most for longevity?
The markers with the strongest evidence for predicting healthspan outcomes: ApoB (atherogenic particle count — superior to LDL-C), Lp(a) (genetically determined cardiovascular risk — order once), fasting insulin (earliest signal of insulin resistance), hsCRP (systemic inflammation), homocysteine (cardiovascular and cognitive risk), Vitamin D, and a full hormone and thyroid panel. These are consistently absent from standard annual bloodwork.